Home Chemistry Heterocyclic Building Blocks Imidazoles 2-Phenylimidazo[1,2-A]Pyridine
Aromatic Substitution: The phenyl ring in 2-phenylimidazo[1,2-a]pyridine can undergo electrophilic aromatic substitution reactions. For example, it can react with electrophiles like nitration (adding a nitro group) or halogenation (adding halogen atoms) under appropriate conditions.
Alkylation and Acylation: The imidazo[1,2-a]pyridine ring system can undergo alkylation or acylation reactions, where alkyl or acyl groups can be added to the nitrogen or carbon atoms within the ring. This typically requires the use of suitable reagents and catalysts.
Nucleophilic Substitution: If there are reactive sites in the molecule, such as halogens or other leaving groups, 2-phenylimidazo[1,2-a]pyridine can undergo nucleophilic substitution reactions. Nucleophiles can displace these groups to form new compounds.
Redox Reactions: Like many organic compounds, 2-phenylimidazo[1,2-a]pyridine can participate in redox reactions. It can be oxidized or reduced under suitable conditions.
Heterocyclic Chemistry: This compound contains a fused heterocyclic ring system. It can participate in various reactions that are characteristic of heterocyclic compounds, such as ring-opening reactions, ring-closing reactions, and transformations of the heterocyclic ring.
Cross-Coupling Reactions: It can participate in cross-coupling reactions with appropriate partners, leading to the formation of new carbon-carbon or carbon-heteroatom bonds.
Formation of Derivatives: By modifying the substituents on the phenyl and imidazo[1,2-a]pyridine rings, various derivatives can be synthesized through chemical reactions. This allows for the creation of compounds with different properties and reactivity.
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6-Chloro-2-phenylimidazo[1,2-a]pyridine
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